Mini IVF, also known as minimal stimulation IVF or micro IVF, is a variation of in vitro fertilization (IVF) that involves a less aggressive approach to ovarian stimulation compared to conventional IVF. It aims to retrieve a smaller number of high-quality eggs while minimizing the use of fertility medications.
Here are the key features of mini IVF:
Ovarian Stimulation: In mini IVF, a lower dose of fertility medications is administered to stimulate the ovaries compared to conventional IVF. The goal is to encourage the growth and maturation of a few high-quality eggs rather than stimulating multiple follicles.
Monitoring: The woman’s natural menstrual cycle or a mild medication protocol is used to monitor the development of follicles. Ultrasound scans and hormone level measurements are performed to track the growth of follicles.
Egg Retrieval: Once the follicles reach an appropriate size and the eggs are deemed mature, an egg retrieval procedure is performed. It is similar to the egg retrieval in conventional IVF, where a thin needle is used to collect the mature eggs from the follicles under ultrasound guidance.
Fertilization: After egg retrieval, the retrieved eggs are combined with sperm in the laboratory. Fertilization can occur naturally, or in some cases, Intracytoplasmic Sperm Injection (ICSI) may be used to assist with fertilization if there are specific concerns.
Embryo Development: The resulting embryos are cultured in the laboratory for a few days to monitor their development. The goal is to obtain high-quality embryos for transfer.
Embryo Transfer: When the embryos have reached an appropriate stage of development, typically at the blastocyst stage, one or more embryos are transferred into the woman’s uterus using a catheter. The embryo transfer procedure is similar to that of conventional IVF.
Luteal Phase Support: Following the embryo transfer, supplemental hormones such as progesterone may be prescribed to support the uterine lining and increase the chances of successful implantation.
Mini IVF is often considered for women who have a lower ovarian reserve or who wish to undergo a more gentle and less medication-intensive fertility treatment. It may be associated with a lower cost compared to conventional IVF due to the reduced need for fertility medications. However, it’s important to note that the success rates of mini IVF may be lower compared to conventional IVF, as the number of eggs retrieved and available embryos for transfer may be limited.
If you’re considering mini IVF, it’s recommended to consult with a fertility specialist who can evaluate your individual circumstances and advise you on the most suitable treatment option for your specific situation.
